https://alex05a.r-universe.devRecent package updates in alex05aR-universehttps://github.com/alex05a.pnghttps://alex05a.r-universe.devTue, 22 Sep 2026 01:42:01 GMTalexandra.gerveni@hotmail.com (Alexandra Gerveni)Detects human-mouse multiplets in patient-derived xenograft (PDX) single-cell RNA-seq data using an adaptive threshold method that does not assume a fixed species proportion. Takes a 10x CellRanger GEM classification file and returns the data with added multiplet classifications, with optional diagnostic plots and helpers to annotate a Seurat or SingleCellExperiment object with multiplet classifications or remove multiplets from it. The adaptive approach starts from a conservative central region of balanced droplets and expands its thresholds until the selected cells no longer resemble true multiplets, which handles the imbalanced species mixtures common in real PDX samples.https://github.com/r-universe/bioc/actions/runs/36795170481Tue, 22 Sep 2026 01:42:01 GMTmultipletR0.99.9successhttps://bioc.r-universe.devhttps://github.com/bioc/multipletRmultipletR-introduction.RmdmultipletR-introduction.htmlDetecting human-mouse multiplets in PDX single-cell data with multipletR2026-07-11 19:02:052026-09-20 21:05:14